Quotulatiousness

February 22, 2018

Dieting and mental health

Filed under: Food, Health — Tags: , — Nicholas @ 05:00

Kaitlin Ugolik discusses her own recent experience of trying a new diet:

We don’t often discuss the mental impact of restrictive diets like Whole30 (no “inflammatory” foods), keto (low carb, high fat) or paleo (foods supposedly eaten during the Paleolithic era). People like to tout the weight loss and mood-boosting effects of these diets, but experts say they can push some of us toward disordered eating.

I tried Whole30 this January, and at first I kind of enjoyed it. I tend to get overwhelmed by options and confused about what’s the latest “right” thing to eat for breakfast, so it was nice to have guidelines. It gave me an excuse to make smoothies and try some new dinner recipes, too.

A few days in, though, I started noticing some disconcerting thoughts. I was reading the labels on everything and starting to think of anything that had any kind of processed sugar — cane sugar, brown rice syrup, anything — as “bad.” I also noticed that some of Whole 30’s carceral language was starting to stick in my head. Foods are labeled as “compliant” or “non-compliant,” for example. Knowing several people who have struggled with eating disorders, I wondered if diets like this, that say you can’t even eat beans or quinoa, might be a gateway to disordered eating for some people. The consensus among the experts I spoke to is that they are.

“All weight-loss diets work against learning to eat ‘normally’ according to appetite cues, which is also called intuitive eating,” said Karen Koenig, a Florida-based social worker who counsels people with eating disorders. “The more we restrict eating—by food type, weighing food, or by counting calories or fat grams—the more we ignore and override our body’s signals for hunger, satisfaction and fullness.”

While some people do benefit from restrictive diets because of their choice-limiting nature, like I did at the beginning, many have a hard time not taking it to the extreme. Most people are taking part in these diets as part of some kind of goal, whether it’s to lose weight, clear up their skin, or just feel better. If (and more likely when) it doesn’t work, it’s normal for anyone to get frustrated. But for people who are already prone to anxiety and obsessive thinking (*raises hand*) or those who have “addictive personalities,” a detox or diet can actually lead to something much more dangerous.

February 18, 2018

The legal loophole that allows profiteering scumbags like Martin Shkreli to gouge the public

Filed under: Bureaucracy, Business, Government, Health, USA — Tags: , , — Nicholas @ 03:00

The US pharmaceutical market is a long way from a freely competitive environment, largely due to the amount of regulatory oversight required by lawmakers and enforced by the Food and Drug Administration (FDA). Among all the regulatory checks and balances, there’s one weird trick that allows predatory companies to reap excess profits legally — the “restricted distribution” loophole:

For immunocompromised adult patients who have the toxoplasmosis parasite, the FDA recommends taking 50 to 75 milligrams of Daraprim a day for up to three weeks, followed by half that dosage for an additional four to five weeks. So at the high end, an adult course of Daraprim therapy for a U.S. patient used to cost around $1,350 total.

While that might not seem cheap, it was a drop in the bucket compared to the cost after Turing Pharmaceuticals, Shkreli’s company, bought the rights to Daraprim and jacked the price up to $750 per pill in 2015. That move increased the cost of one course of treatment to around $75,000.

At that point you might have expected another company to jump in and start offering a generic version of the drug. But Shkreli used a regulatory loophole to keep that from happening.

You see, when a generic manufacturer wants to create a cheap version of a branded drug, it has to buy thousands of doses from the manufacturer in order to run comparison tests. Generic manufacturers use the results of these tests to prove to the FDA that their version is identical to the branded drug that the agency has already approved.

More often than not, the company that holds the marketing and distribution rights to a branded drug will sell those comparison doses to the generic manufacturer without being obstructionist, because that’s the trade-off for receiving a 20-year monopoly by way of a drug patent: The branded manufacturer gets to charge whatever they want for years and years without facing competition, and in exchange for that government-backed monopoly, it’s supposed to sell equivalency samples to generic companies.

But what if the company is run by an unscrupulous asshole like Martin Shkreli? Then it might opt to put the drug into what’s called “restricted distribution,” which means no distributor anywhere can sell comparison samples to a generic manufacturer.

The FDA originally created the concept of restricted distribution to limit the availability of drugs that might be dangerous. Methadone, for instance, was first approved in the 1940s as a painkiller. In the 1970s, the FDA restricted its availability because regulators didn’t want the opioid used for anything other than the treatment of opioid dependence. Even today, methadone can be dispensed only in highly regulated settings and only for one approved reason.

In 2007, Congress empowered the FDA to create an entire system of safety controls beyond restricted distribution, and the agency now requires the manufacturers of certain substances to develop Risk Evaluation and Mitigation Strategies (REMS) to prevent misuse and abuse of potentially problematic compounds.

The list of approved drugs that the FDA says must have an REMS is here. Daraprim is not on that list. You can’t get high off it. It’s not habit forming. Yes, the FDA label says it can be carcinogenic after long periods of use, and that it might cause birth defects if used in high doses by pregnant women. These potential effects are serious, but there is no post-market data suggesting that Daraprim is causing more harm than benefit in the intended patient population. Shkreli’s company put Daraprim into restricted distribution to boost their profits, not protect patients.

February 11, 2018

Bay area food entrepreneurs shut down by local health authorities

Filed under: Business, Food, Government, Health, Technology, USA — Tags: , , — Nicholas @ 03:00

In Reason, Baylen Linnekin recounts the rise and fall of Josephine, an online operation intended to connect home cooks with willing buyers:

A dozen or so years ago, as my friend Dave was planning a move from Washington, D.C., to Philadelphia, he used the need to clean out his fridge before the move as an excuse to offer a half-empty jar of homemade kimchi for sale on Craigslist. While I don’t think the kimchi sold, Dave’s effort opened my eyes to the seemingly limitless possibilities of homemade online food sales.

The truth is that while those possibilities are limited theoretically only by imagination, they very often bump up in the real world against — to paraphrase Waylon Jennings — the limits of what the law will allow.

That truth was evident last week, when Bay Area food startup Josephine announced it will close its doors in March.

As I described in a Sacramento Bee op-ed in support of Josephine last year, the company launched nearly four years ago with a mission to provide cooks who are typically underrepresented in restaurant leadership — including women and immigrants — with a platform by which to sell home-cooked meals with their neighbors.

It’s a cool idea. And it worked quite well for a time. That is, as I noted, until local health officials “sent cease-and-desist letters to several Josephine cooks.”

Josephine responded by trying to work with lawmakers and regulators, pushing a bill in the state legislature that would provide some legal avenue for its cooks. Despite the fact that the bill is now moving through the California legislature, the company decided its passage would be too late for Josephine and its funders.

Josephine didn’t have to die. The regulations that have made it impossible for the company to operate should have died instead. But its fate mimics that of other similar home-food startups. A similar New York-based startup, Umi Kitchen, flamed out last year after just four months of operations. I wrote an appreciation of Forage Underground Market, the inventive San Francisco food swap that was shuttered by California state and local health authorities, way back in 2012. And I predicted at the time the food underground movement was just beginning to blossom.

February 7, 2018

Better Safe than Sorry! l THE HISTORY OF CONTRACEPTION

Filed under: Health, History — Tags: , , — Nicholas @ 02:00

IT’S HISTORY
Published on 26 Sep 2015

The development of contraceptives has come a long way. It all started with questionable ointments and rituals to avoid pregnancy. The effectiveness of new inventions have since improved greatly. Especially the invention of rubber and latex for condoms or contraceptive ideas like the diaphragm or the pill. Learn about the development of contraceptives and their societal standing this episode on IT’S HISTORY.

February 3, 2018

Arizona’s legally protected blow-drying cartel

Filed under: Business, Government, Health, USA — Tags: , , , — Nicholas @ 05:00

Eric Boehm reports on the fantastic lengths protected businesses will go to to protect themselves from “unlicensed” competitors, even in such areas as hair drying:

Brandy Wells never anticipated the amount of vitriolic abuse she would receive over — of all things — her public support of a proposal to let people blow-dry hair without a state-issued license.

“I’ve been called a cunt, a bitch, an ass, trashy, a puppet, a pawn, repugnant,” Wells says. “And my favorite: ‘your logic on deregulation of cosmetology is much like your hair, dull and flat.'”

Wells says she’s received several attacks from cosmetologists on social media accusing her of being “uneducated” or “clueless” about cosmetology because she doesn’t work in the industry. It’s true that Wells isn’t a licensed cosmetologist (though she does, in fact, know how to use a blow-dryer, she confirmed to Reason), but that’s actually the precise reason why she’s speaking up.

Wells serves as the lone “public member” of the Arizona State Board of Cosmetology. That means she is the only member of the seven-person board who does not work in some capacity as a cosmetologist or with a connection to a cosmetology school. Last month, she voiced her support for House Bill 2011, which would removing blow-drying from the state’s cosmetology licensing requirements. Under current law, using a blow-dryer on someone else’s hair, for money, requires more than 1,000 hours of training and an expensive state-issued license. Blow-drying hair without a license could — incredibly — land you in jail for up to six months.

In response, Wells says, members of the cosmetology profession have sent messages to her employer, the Arizona Chamber of Commerce, suggesting that she should be fired — fired because she thinks people can safely blow-dry hair without 1,000 hours of training!

The cosmetology board is “a group of special interest bullies,” said Arizona Gov. Doug Ducey, a Republican, in his recent State of the State address. The board, Ducey said, “is going after people who simply want to make a living blow-drying hair. No scissors involved.”

This week, the fight over the so-called “blow-dry bill” spilled into the state legislature. The state House Military, Veterans, and Regulatory Affairs Committee held its first hearing on the bill, and licensed cosmetologists packed the room to speak one-by-one about the potential dangers of letting unlicensed professionals blow-dry hair

The logical endpoint of socialized medicine

Filed under: Britain, Government, Health — Tags: , — Nicholas @ 03:00

In the Guardian, Nick Cohen explains what Brits will need to do to maintain the National Health Service as their key defining national institution:

If you imagine a healthy future for Britain, or any other country that has put the hunger of millennia behind it, you see a kind of dictatorship. Not a tyranny, but a society that ruthlessly restricts free choice. It is a future that views the mass of people as base creatures jerked around by desires they cannot control. Expert authority must engineer their lives from above for their own good and the common good.

The one who pays the piper calls the tune, and when it’s the government paying the need to keep healthcare costs down will first encourage and later mandate more and more restrictions on the freedoms of the people. Oddly, although he starts out strongly, the rest of the piece falls short of the more stringent restrictions that logic would dictate, concentrating on the relative trivia of expanding pedestrian and bicycle access to downtown areas and corresponding restrictions to private vehicles, plus moving fast food outlets further away from schools.

I can feel the force of the objections. When we imagine a healthier future we are also imagining a more authoritarian state. Individual choice will be constrained and wisdom of the crowd rejected. Women will wonder who will chop the vegetables and cook the dinners when ultra-processed food is taxed to the point of extinction.

Beyond gender lies an undoubted class element in public health campaigns. Sugar and fat addiction, like all addictions, provide a temporary respite for the poor, the depressed and the disappointed. Perhaps we should offer them better lives rather than snatch away the few comforts they enjoy. This sounds a stirring counter-argument. But as any reader who has been an addict will know, addiction prevents you finding a better life. For when you suffer the multiple morbidities of diabetes, arthritis, cancer and strokes, your sicknesses are your life. You do not have the freedom to choose to change it.

God knows, there are good reasons to mistrust experts re-engineering societies from above. But as with tobacco, freedom of choice in the food and car markets has left us with no choice but to trust them.

To safeguard the NHS from bankruptcy, the government will end up looking at quite draconian efforts to reduce or eliminate risks to public health (generously interpreted). First the minor nudges, like raising the prices of alcoholic beverages and tobacco products to discourage smoking and drinking, then perhaps the same for whatever foods are currently considered to be Public Enemy Number One (last year it was fat, this year it’s sugar, next year it might be carbohydrates in general). Then, when the nudges haven’t achieved their intended ends, harsher measures are called for and will need to be implemented over a wider range of products, services and activities, as human beings have an amazing capability to sidestep or avoid what their betters want for them. Exercise will be first encouraged, then demanded, and finally required. Dangerous activities will first be discouraged, then penalized, then finally outlawed.

We’ve already seen the beginnings of the move from mere nudges to more open control, as smokers and the obese are starting to face restrictions on their access to the NHS until they show more than a token obedience to medical authority. Your doctor will slowly morph from mere caregiver to guardian to overseer. All in the name of public health, of course.

H/T to Natalie Solent for the original link.

February 1, 2018

Penn and Teller on Vaccinations

Filed under: Health, Science, USA — Tags: , , , — Nicholas @ 02:00

UltraMiraculous
Published on 20 Aug 2010

January 13, 2018

The common factor of the Net Neutrality fight and the EpiPen price gouging scandal

Filed under: Bureaucracy, Economics, Government, Health, Technology, USA — Tags: , , , , — Nicholas @ 05:00

Lili Carneglia explains what these two examples of “capitalist excess” are actually the result of regulatory failures:

Without net neutrality, regulations that prevent internet service providers (ISPs) from charging more for priority speeds and higher bandwidth-use sites would disappear. Most Americans are pretty confused by the revised rules but highly skeptical that this action could have any benefits. Many people, especially those living in the rural south where choices are limited, feel like these companies have been taking advantage of their customers for years, and loosening regulatory constraints on these companies seems like a terrible idea.

Net neutrality was a regulatory policy set under the Obama administration in 2015 that mandated ISPs to treat the internet like other utilities, such as highways and railroads, under laws established before most people had TVs. Under these rules, companies must act as neutral gateways to the internet without controlling the content or the speed of the content that passes through that gateway. Supporters of the rule argue that these regulations ensure the free flow of information, while those against the policy see net neutrality as a misapplication that stifles an industry that is more dynamic than other public utilities.

[…]

Yes, a handful of industry giants can and have abused their market power. Most consumers have limited ISPs to choose from in a given area, and options are more limited outside of big cities, where “three-quarters of American homes have no competitive choice for the essential infrastructure for 21st-century economics and democracy,” according to the former FCC chairman Tom Wheeler. It is important to consider how these circumstances came about before deciding that federal regulation might help consumers.

Governments, by and large, prefer to have fewer players in a given market as it makes that market easier to regulate, and the easiest market to regulate is a monopoly. When cable networks were beginning to spread across North America, many local governments were persuaded that a single cable provider would be the best option for their jurisdiction and the broadband internet market that came later was heavily shaped by the already carved-up markets for cable TV. For many, there were no competitive options because the local government had precluded the chance of competition for their already entrenched cable monopoly (or, in a few cases, tight oligopoly).

Competition is the best answer to monopolistic abuse of customers … if you get shitty service from the Blue Cable Company, you’ll be more likely to switch to the Red Cable Company. If you only have Red and Blue to choose from, your leverage is small, but if you have a full rainbow of competing options, Red and Blue are forced to make their services at least comparable to what Orange and Pink and Magenta are offering, or they lose too many customers. If there’s no threat of a competitor scooping up unhappy customers, there’s no incentive for the existing company to do more than the absolute minimum to keep customer complaints down to a dull roar. The customer’s only recourse — other than giving up the service or moving to a different jurisdiction — is to complain to the regulator.

The base problem with Mylan’s EpiPen price gouging is the same: an effective monopoly supported by the government:

The arguments against net neutrality repeals center around fears about what producers will do without regulation since they have significant market power and the ability to raise prices to levels that would not be sustainable under more competitive conditions. The concern about increased internet prices is similar to what happened in 2016 when a pharmaceutical company with market power, Mylan, increased the price of life-saving EpiPens by about 400 percent.

The “greedy” pharmaceutical companies were hung out to dry as Congress berated Mylan representatives in hearing after hearing. There were similar cries of outrage and demands that the federal government do something to prevent such selfish price-gouging, similar to what many consumers fear ISPs will do absent regulations.

Even (supposed) free-market advocates started supporting further regulation during the EpiPen debate. Most notably, then fiscal hawk representative and now Trump budget director Mick Mulvaney, defended further market intervention on the condition that, “If you want to come to the state capitols and lobby us to make us buy your stuff, this is what you get. You get a level of scrutiny and a level of treatment that would ordinarily curl my hair.”

However, in all of those hearings, almost no one bothered to unearth the problem that Mulvaney hinted at: Why was Mylan able to increase that price in the first place? Government intervention. Burdensome FDA regulations and other laws pressuring public schools to buy the drug essentially granted Mylan a monopoly. It was as misguided then as it is now to think that these same institutions can be trusted to clean up the mess they created.

Mylan had no effective competition, so there was nothing to stop the price gouging until it got so bad that even the regulator had to pay attention. If there were other pharmaceutical companies allowed to compete, do you think Mylan would have risked jacking up the price only to watch their competitors gaining market share?

Scott Alexander explained the Mylan monopoly quite expansively in 2016.

January 8, 2018

Sex is a Basic Instinct – Sigmund Freud l HISTORY OF SEX

Filed under: Health, History — Tags: , , , — Nicholas @ 02:00

IT’S HISTORY
Published on 30 Sep 2015

The psychologist Sigmund Freud spent much of his life trying to understand how the human psyche functions. Famously sorting the human consciousness into the it, the ego and the superego. He was particularly interested in the instinct for sex and satisfaction of lust, a phenomenon he called the libido. Many of his theories were highly disputable, such as his theory on infantile sexuality and the societal influence on sexuality. Learn all about the father of psychoanalysis on ITS HISTORY!

January 7, 2018

Give your butt a wake-up call with the latest from “Gwyneth Paltrow’s life-threatening, wallet-flensing empire of woo”

Filed under: Business, Health, Media, USA — Tags: , , , , , — Nicholas @ 03:00

Cory Doctorow views with alarm yet another potentially dangerous product from Goop:

Goop is Gwyneth Paltrow’s life-threatening, wallet-flensing empire of woo, home to smoothie dust, vulva steaming, rocks you keep in your vagina, and a raft of rebadged products that are literally identical to the garbage Alex Jones sells to low-information preppers.

Both Goop and Alex Jones are big on “detoxing,” an imaginary remedy that poses a very real health-risk, especially when it involves filling your asshole with coffee.

Coffee enemas are, of course, bullshit, whose history and present are rife with hucksters whose smooth patter is only matched by their depraved indifference for human life.

But as stupid as coffee enemas are, they’re even stupider when accomplished by means of Goop’s, $135 “Implant O’Rama,” manufactured by Implant O’Rama LLC. It’s a $135 glass jar with a couple silicon hoses attached to it.

December 27, 2017

QotD: Psychology

Filed under: Health, Humour, Quotations — Tags: , , — Nicholas @ 01:00

Psychology is nothing at all like a science and those who practice it are nothing at all like scientists. Mostly they’re liberals. No two shrinks ever agree on a diagnosis, and official definitions of various mental illnesses are a grammatical and logical laugh riot. The great truth of life is that understanding character is an art, best left to master novelists and story-tellers.

L. Neil Smith, “Why the Left-Wing Seems Insane (Mostly Because They Are)”, Libertarian Enterprise, 2016-05-08.

December 13, 2017

Why do we have Pubic Hair? – BRITLAB

Filed under: Health — Tags: , — Nicholas @ 02:00

BBC Earth Lab
Published on 18 Dec 2014

Contains adult themes. Greg Foot looks at why humans have pubic hair – investigating the hormones that cause growth, and the benefits of shaving vs letting it grow.

December 10, 2017

QotD: Failures of scientific consensus

Filed under: Health, History, Quotations, Science — Tags: , , , — Nicholas @ 01:00

In past centuries, the greatest killer of women was fever following childbirth. One woman in six died of this fever. In 1795, Alexander Gordon of Aberdeen suggested that the fevers were infectious processes, and he was able to cure them. The consensus said no. In 1843, Oliver Wendell Holmes claimed puerperal fever was contagious, and presented compelling evidence. The consensus said no. In 1849, Semmelweiss demonstrated that sanitary techniques virtually eliminated puerperal fever in hospitals under his management. The consensus said he was a Jew, ignored him, and dismissed him from his post. There was in fact no agreement on puerperal fever until the start of the twentieth century. Thus the consensus took one hundred and twenty five years to arrive at the right conclusion despite the efforts of the prominent “skeptics” around the world, skeptics who were demeaned and ignored. And despite the constant ongoing deaths of women.

There is no shortage of other examples. In the 1920s in America, tens of thousands of people, mostly poor, were dying of a disease called pellagra. The consensus of scientists said it was infectious, and what was necessary was to find the “pellagra germ.” The US government asked a brilliant young investigator, Dr. Joseph Goldberger, to find the cause. Goldberger concluded that diet was the crucial factor. The consensus remained wedded to the germ theory. Goldberger demonstrated that he could induce the disease through diet. He demonstrated that the disease was not infectious by injecting the blood of a pellagra patient into himself, and his assistant. They and other volunteers swabbed their noses with swabs from pellagra patients, and swallowed capsules containing scabs from pellagra rashes in what were called “Goldberger’s filth parties.” Nobody contracted pellagra. The consensus continued to disagree with him. There was, in addition, a social factor — southern States disliked the idea of poor diet as the cause, because it meant that social reform was required. They continued to deny it until the 1920s. Result — despite a twentieth century epidemic, the consensus took years to see the light.

Probably every schoolchild notices that South America and Africa seem to fit together rather snugly, and Alfred Wegener proposed, in 1912, that the continents had in fact drifted apart. The consensus sneered at continental drift for fifty years. The theory was most vigorously denied by the great names of geology — until 1961, when it began to seem as if the sea floors were spreading. The result: it took the consensus fifty years to acknowledge what any schoolchild sees.

And shall we go on? The examples can be multiplied endlessly. Jenner and smallpox, Pasteur and germ theory. Saccharine, margarine, repressed memory, fiber and colon cancer, hormone replacement therapy. The list of consensus errors goes on and on.

Finally, I would remind you to notice where the claim of consensus is invoked. Consensus is invoked only in situations where the science is not solid enough. Nobody says the consensus of scientists agrees that E=mc2. Nobody says the consensus is that the sun is 93 million miles away. It would never occur to anyone to speak that way.

Michael Crichton, “Aliens Cause Global Warming”: the Caltech Michelin Lecture, 2003-01-17.

December 9, 2017

QotD: Staying beautiful

Filed under: Health, Quotations — Tags: , , — Nicholas @ 01:00

To understand what it takes to be beautiful, we need to be very clear about what being beautiful means — being sexually appealing to men. And then, instead of snarling that male sexuality is evil, we need to accept that it’s just different — far more visually-driven than female sexuality. To focus our efforts, we can turn to an increasing number of studies by evolutionary psychologists on what most men seem to want. For example, the University of Texas’ Devendra Singh discovered that men, across cultures, are drawn to a woman with an hourglass figure. Men like to see a woman’s waist — even on the larger ladies — so burn those muumuus, which only reveal your girlish figure in a Category 5 hurricane, and if you don’t have much of a waist, do your best to give yourself one with the cut of your clothes or a belt.

Too many women try to get away with a bait-and-switch approach to appearance upkeep. If you spend three hours a day in the gym while you’re dating a guy, don’t think that you can walk down the aisle and say “I do…and, guess what…now I don’t anymore!” A woman needs to come up with a workable routine for maintaining her looks throughout her lifetime and avoid rationalizing slacking off — while she’s seeking a man and after she has one. Yeah, you might have to put five or ten extra minutes into prettying up just to hang around the house. And, sure, you might be more “comfortable” in big sloppy sweats, but how “comfortable” will you be if he leaves you for a woman who cares enough to look hot for him?

Like French women, we, too, need to understand that a healthy approach to beauty is neither pretending it’s unnecessary or unimportant nor making it important beyond all else. By being honest about it, we help women make informed decisions about how much effort to put into their appearance — or accept the opportunity costs of going ungroomed. The truth is, like knowledge, beauty is power. So, ladies, read lots of books, develop your mind and your character, exercise the rights the heroes of the women’s movement fought for us to have, and strive to become somebody who makes a difference in the world. And, pssst…while you’re doing all of that, don’t forget to wear lipgloss.

Amy Alkon, “The Truth About Beauty”, Psychology Today, 2010-11-01.

December 8, 2017

QotD: Why mid-20th century Americans ate what they did – 7

Filed under: Economics, Food, Health, History, Quotations, USA — Tags: , — Nicholas @ 01:00

Entertaining was mandatory [in the 1950s]. Because people didn’t go to restaurants so much, they spent time having people over, or eating at someone else’s house. If someone had you over, you had to have them over. This meant people had to have “company dinners” they could make, or at least a stock of canapés they could throw together for a cocktail party, even if they weren’t very good at it. Cue the weird focus on prettying everything up, more than occasionally to the detriment of the food itself: if you can’t make it good, you can at least make it pretty, to show people you made an effort.

Megan McArdle, “Friday Food Post: The Economics Behind Grandma’s Tuna Casseroles”, Bloomberg View, 2015-10-30.

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