Quotulatiousness

March 28, 2012

Speaking of science, here’s a new development in “thermal cloaking”

Filed under: France, Science, Technology — Tags: , — Nicholas @ 09:42

Lewis Page at The Register walks us through the high points of a new development from France:

Top boffins in France have come up with a radical new take on the “cloaking” and invisible-shed physics breakthroughs of recent years. They have designed a technology which instead of bending microwaves or light can shield an object from heat — or concentrate heat upon it.

“Our key goal with this research was to control the way heat diffuses in a manner similar to those that have already been achieved for waves, such as light waves or sound waves,” says Sebastien Guenneau, of Aix-Marseille uni and France’s Centre National de la Recherche Scientifique (CRNS).

“Heat isn’t a wave — it simply diffuses from hot to cold regions,” Guenneau adds. “The mathematics and physics at play are much different.”

For now designed only in two dimensions, Guenneau and his colleagues’ approach involved shaping isotherms — lines showing density of heat flux transferring from point — so as to make heat travel around a given area rather than into it.

“We can design a cloak so that heat diffuses around an invisibility region, which is then protected from heat. Or we can force heat to concentrate in a small volume, which will then heat up very rapidly,” Guenneau says.

March 10, 2012

Some diseases may be caused by “endogenous” retrovirii

Filed under: Health, Science — Tags: , , , , — Nicholas @ 12:17

Matt Ridley on some recent discoveries in genetics and medicine that may help to explain certain diseases like multiple sclerosis:

The virus implicated in multiple sclerosis is called HERV-Fc1, a bizarre beast called an “endogenous” retrovirus. What this means is that its genes are part of the human genome. For millions of years, they have been integrated into our own DNA and passed on by normal heredity. It was one of the shocks of genomic science to find that the human genome contains more retroviral than “human” genes: some 5% to 8% of the entire genome.

Normally, the genes of endogenous retroviruses remain dormant, but — a bit like a computer virus that springs into action on a trigger — something wakes them up sometimes, and actual viruses are made from them, which then infect other cells in the body. The Danish scientists suggest that this is what happens in multiple sclerosis. Bjørn Nexø of Aarhus University writes that “retroviral infections often develop into running battles between the immune system and virus, with the virus mutating repeatedly to avoid the immune system, and the immune system repeatedly catching up. One can see the episodic nature of multiple sclerosis as such a running battle.”

The possibility that you can inherit the genes of a virus blurs the distinction between a genetic and an infectious disease. The HERV-Fc1 genes lie on the X chromosome. Since women have twice as many X chromosomes as men, this might explain why some forms of MS are more common in women. Dr. Nexø concludes hopefully: “The finding that a disease is caused by an infectious agent is an encouraging one. These are the diseases which we know best how to treat.

The research also appears to show a link between cat ownership and schizophrenia:

Human beings can also catch toxoplasma from cats, and it’s known to affect behavior: altering personalities, slowing reaction times and increasing the risk of car accidents. More than 20 studies have now found an association between schizophrenia and toxoplasma. Schizophrenia is more common among those who had pet cats in their childhood homes (but not in those who had pet dogs).

Indeed, some scientists think that schizophrenia only became common, around 1870, when keeping cats as indoor pets became fashionable. The parasite has genes for dopamine, a neurochemical found in excess in schizophrenics.

February 25, 2012

Tim Harford: The problem of “interdisciplinary problems”

Filed under: Economics, Science, Technology — Tags: , , , — Nicholas @ 10:25

Tim Harford recently visited Oxford Martin School to discuss the phenomenon of problems that are seen as intractable when viewed from within a “silo” or single discipline, but which yield solutions when approached in co-operation with multiple disciplines:

In academia, the challenge of encouraging interdisciplinary research is at least recognised as a problem. The advancing frontier of scientific knowledge forces most researchers to specialise in ever narrower fields and, as a result, collaboration between these silos is essential. I recently visited the Oxford Martin School, a seven-year-old initiative designed to foster cross-disciplinary projects at the University of Oxford. I talked to the school’s director, Ian Goldin, about the challenges of breaking down academic silos.

He thinks these silos are mostly artificial. Academic journals are largely specialised rather than interdisciplinary and official funding bodies shy away from interdisciplinary projects. The result is that academics with interdisciplinary interests have few ways to fund the research and few credible outlets for publishing the results. The Martin School has funding, but most of the researchers are either junior, with some freedom to experiment, or professors so senior they no longer need to worry about their publication record. The mid-career academics are missing. It is nice to hear the tenure system sometimes produces the hoped-for courage and independence, but not so nice that there is no career track for interdisciplinary researchers.

[. . .]

If problems are one focal point for collaboration, tools can be another. An example: systems needed to deal with the gigantic data sets generated in finance, astronomy and oceanography. Such tools naturally bring together computer scientists and the statisticians, economists and scientists who might use the data. Goldin points to “crowdsourcing” as a second example of a cross-disciplinary tool, complexity science as a third and (optimistically, I feel) practical ethics as a fourth.

Perhaps the real lesson is that promoting cross-disciplinary research need not require a mysterious blend of social-networking tools and funky collaborative architectural spaces. All that is sometimes required is a shared problem, or a shared set of tools, and, above all, the money to pay for the job to be done.

February 14, 2012

Envisioning the all-online university

Filed under: Media, Technology — Tags: , , , — Nicholas @ 09:56

Megan McArdle on the recent announcement that MIT will be offering online programs (at lower cost than regular courses) and if this is a sign of the future (as it almost certainly is) what changes will occur in the realm of higher education:

I can see all sorts of factors that might combine to preserve the status quo, from signaling and status and networking, to the desire of college students for a four-year debt-financed semi-vacation. On the other hand, disruption never looks inevitable until it suddenly is — if you’d told someone in 1955 that GM was going to have its lunch eaten by some Japanese upstart, they would have laughed until the tears came. So it’s interesting and maybe even useful to contemplate what the college system would look like if this sort of distance learning becomes the norm.

1. Education will end up being dominated by a few huge incumbents. [. . .]

2. Online education will kill the liberal arts degree. [. . .]

3. Professors (course developers) will be selected for teaching instead of research brilliance. [. . .]

4. 95% of tenure-track professors will lose their jobs. [. . .]

5. The corollary of #4 is the end of universities as research centers. [. . .]

6. Young job-seekers will need new ways to signal diligence. [. . .]

7. The economics of graduate school will change substantially. [. . .]

8. Civil society will have to substitute for the intense friend networks that are built at college. [. . .]

9. The role of schooling in upward mobility will change. [. . .]

10. The young will have a much lower financial burden in their 20s. [. . .]

11. The tutoring industry will boom. [. . .]

12. If the credentials become valuable, cheating will be a problem. [. . .]

February 11, 2012

Yet another theory on the solar effect on the Earth’s climate

Filed under: Environment, Science, Space — Tags: , , — Nicholas @ 12:14

You’d automatically assume that the sun is a major factor in the climate, but this theory is non-intuitive:

That man is the Danish physicist Henrik Svensmark, who seems to have discovered the most important factor that actually regulates Earth’s climate, and who is quietly in the process of proving it.

[. . .]

Let me briefly sum up Svensmark’s theory. The temperature of the Earth, he argues, is regulated by the intensity of solar radiation, but not in the obvious way. It is not that the increase is solar radiation heats the Earth directly. (It does, of course, but not to a sufficient degree to explain climate variations.) Rather, an increase in solar radiation extends the Sun’s magnetic field, which shields Earth from cosmic rays (highly energetic, fast-moving charged particles that come from deep space). How does this affect the climate? Here is the crux of Svensmark’s argument. When cosmic rays hit the atmosphere, he argues, their impact on air molecules creates nucleation sites for the condensation of water vapor, leading to an increase in cloud-formation. Since clouds tend to bounce solar radiation back into space, increased cloud cover cools the Earth, while decreased cloud cover makes the Earth warmer.

So if Svensmark is right, lower solar radiation means more cosmic rays, more clouds, and a cooler Earth, while higher solar radiation means fewer cosmic rays, fewer clouds, and a warmer Earth.

Those who have followed the global warming controversy over the years may recall that cloud-formation is one of the major gaps in the computerized climate “models” used by the consensus scientists to predict global warming. They have never had a theory to explain how and why clouds form or to account accurately for their effect on the climate. Svensmark has smashed through this glaring gap in their theory.

February 10, 2012

Willpower, for good or evil

Filed under: Books, Media, Science — Tags: , , — Nicholas @ 11:52

In the Guardian, Jon Henley reviews the new book by Roy F Baumeister and John Tierney:

Willpower: Rediscovering Our Greatest Strength distills three decades of academic research (Baumeister’s contribution) into self-control and willpower, which the Florida State University social psychologist bluntly identifies as “the key to success and a happy life”.

The result is also (Tierney’s contribution) readable, accessible and practical. It’s an unusual self-help book, in fact, in that it offers not just advice, tips and insights to help develop, conserve and boost willpower, but grounds them in some science.

Willpower is, Baumeister argues over lunch, “what separates us from the animals. It’s the capacity to restrain our impulses, resist temptation — do what’s right and good for us in the long run, not what we want to do right now. It’s central, in fact, to civilisation.”

The disciplined and dutiful Victorians, all stiff upper lip and lashings of moral fibre, had willpower in spades; as, sadly, did the Nazis, who referred to their evil adventure as the “triumph of will”. In the 60s we thought otherwise: let it all hang out; if it feels good, do it; I’m OK, you’re OK.

But without willpower, it seems, we’re actually rarely OK. In the 60s a sociologist called Walter Mischel was interested in how young children resist instant gratification; he offered them the choice of a marshmallow now, or two if they could wait 15 minutes. Years later, he tracked some of the kids down, and made a startling discovery.

[. . .]

What they found was that, even taking into account differences of intelligence, race and social class, those with high self-control — those who, in Mischel’s experiment, held out for two marshmallows later — grew into healthier, happier and wealthier adults.

January 30, 2012

Researching how to stop asteroids from “just dropping in”

Filed under: Europe, Science, Space, Technology — Tags: , , , — Nicholas @ 10:08

Brid-Aine Parnell in The Register on some of the technologies being explored to reduce or eliminate the chance of unpleasantly close encounters with celestial objects:

A new international consortium has been set up to figure out what Earthlings could do if an asteroid came hurtling towards the planet on a path of imminent destruction.

The project will look at three methods of averting disaster: the Hollywood-sanctioned solutions of sending up a crack team of deep drillers with a nuclear bomb to sort it out, or frantically hurling of all our nukes at it; dragging it to safety with a Star Trek-inspired tractor beam; or hitting it with something we have more control over, like a spaceship.

Sporting the cool moniker NEOShield, the project will explore the possibilities for kinetic impactors, gravity tractors and blast deflection as ways to save our planet from oblivion.

[. . .]

“In the light of results arising from our research into the feasibility of the various mitigation approaches and the mission design work, we aim to formulate for the first time a global response campaign roadmap that may be implemented when an actual significant impact threat arises,” NEOShield boldly stated.

The anti-Moonbase chorus

Filed under: Space, USA — Tags: , , , — Nicholas @ 09:46

Natalie Rothschild on the (non-political) opposition to the very notion of a manned space program:

Suspicion towards space exploration is not new, of course. Since the 1970s, it has variously been decried as a danger to peace and security, as a chauvinist enterprise, as a wasteful pursuit and as a threat to the environment. Yet pessimism and indifference to space discoveries are at an all-time high today. This became clear in the reaction — or lack of reaction, rather — to NASA’s announcement in December 2009 that water had been discovered on the moon. As Sean Collins pointed out on spiked at the time, this was ‘a giant leap towards fulfilling one of our collective fantasies, something only dreamed about in science fiction: humans living somewhere other than Earth’. It also made the moon a more likely base for manned missions to other parts of the solar system and NASA suggested the lunar water could hold a key to the history and evolution of the solar system. Yet, as Collins pointed out then, neither online pundits nor the mainstream media nor the authorities made a big deal out of the ground breaking discovery.

Seen in this context it was no surprise that Gingrich’s boasts were ridiculed. His plans for a space colony might have sounded like a good idea when he touted it to Florida’s struggling Space Coast. After all, when the Obama administration cancelled George W Bush’s plans to return American astronauts to the moon by 2020, it prompted protests from the communities that depend on NASA for their livelihood as well as from Apollo veterans. But it was no surprise that he was met with put-downs from most other quarters and that his ideas were entirely dismissed.

By and large, human achievements tend to be downplayed today. Exploring the unknown is seen as, at best, impractical and, at worst, reckless. When it comes to manned space exploration, the prevailing attitude is ‘been there, done that’. That’s why there’s been an unwillingness to separate Gingrich’s more wacky ideas — launching a new space race and establishing a permanent American outpost on the moon within eight years — from his sensible reminder that if we are to have any chance of making new discoveries and advances in the near or distant future, then we need to be willing at least to imagine that it’s possible and desirable to overcome the limits we face today.

January 29, 2012

Coffee may help in weight loss (but your gallon-sized hippy-dippy frappy latté certainly won’t)

Filed under: Health, Science — Tags: , — Nicholas @ 12:30

A brief news item at 680news.com:

New research has found coffee may have many health benefits, including moderate weight loss.

James O’Keefe, a cardiologist with St. Lukes medical system, says a review of some of the largest studies on coffee consumption found it contains anti-oxidants which are widely believed to be good for your health.

He added that, despite the fact that coffee has been shown to increase blood pressure and heart rate, the caffeine can actually aid in the prevention or delay of Type 2 diabetes.

Compounds in your morning cup of joe can increase insulin and reduce inflammation, as well we increasing your metabolism at the cost of no calories.

Just for the folks who think coffee is something you pay $5.00 plus tax for at your local Starbucks: this is the no-cream, no-sugar, no-syrup, no-whipped-cream, no-sprinkles hot beverage you don’t need to buy in imaginatively named cup sizes.

Thanks for the memories, oligomers

Filed under: Health, Science — Tags: — Nicholas @ 12:21

A recent discovery at the Stowers Institute for Medical Research may indicate fruitful directions for further research on memory loss:

Memories in our brains are maintained by connections between neurons called “synapses.” But how do these synapses stay strong and keep memories alive for decades? Neuroscientists at the Stowers Institute for Medical Research have discovered a major clue from a study in fruit flies: Hardy, self-copying clusters or oligomers of a synapse protein are an essential ingredient for the formation of long-term memory.

The finding supports a surprising new theory about memory, and may have a profound impact on explaining other oligomer-linked functions and diseases in the brain, including Alzheimer’s disease and prion diseases.

“Self-sustaining populations of oligomers located at synapses may be the key to the long-term synaptic changes that underlie memory; in fact, our finding hints that oligomers play a wider role in the brain than has been thought,” says Kausik Si, Ph.D., an associate investigator at the Stowers Institute, and senior author of the new study, which is published in the January 27, 2012 online issue of the journal Cell.

January 17, 2012

To help kids stay healthier, don’t be a clean fanatic

Filed under: Health, Science — Tags: , , , — Nicholas @ 12:08

I’ve suspected for quite a while that the “epidemic” of food allergies and other ailments among today’s children was related to the extremely hygienic conditions of modern homes (that is, kids’ immune systems were insufficiently stressed by exposure to germs, which meant higher risk of immune system over-reaction later in life). I’m not a scientist, so my suspicion was just based on less-than-statistically valid observation of my son and his friends while they were growing up — the kids with the most sterile home environments did seem more likely to have serious allergy issues come up later.

I could have been on the right track, after all:

I do wonder, however, whether we’re all becoming a bit too paranoid about germs. I include my own family in this group. Once we left the doctors’ office, for example, my wife and I encouraged our children to use a hand sanitizer. When our kids were toddlers our house had alcohol wipes and Purell vials all over the place. But is all this washing and disinfecting really necessary? Is it proactive prevention? Or overly paranoid fear?

That, at least, is the thinking behind the “hygiene hypothesis,” a school of thought first proposed by David P. Strachan in 1989, and now experiencing a resurgence that’s probably a response to society’s mania for cleanliness. Strachan’s original study sought to explain why British kids with greater numbers of older siblings had fewer incidences of hay fever, speculating that perhaps it could be the fact kids with lots of older siblings tend to be exposed to greater numbers of germs. While it was greeted with skepticism early on, Strachan’s theory has since been confirmed. In fact, in the decades since, greater exposure to germs early in life has also been associated in epidemiological studies with lower levels of asthma, some allergies and even such autoimmune diseases as type-1 diabetes and multiple sclerosis.

[. . .]

“These data support the idea that the greater diversity of microbial exposure among children who live on farms is associated with the protection from the development of asthma,” study researchers reported, speculating that microbial exposure may encourage development of immune system cells that in turn suppress the production of the sort of immune-system cells that trigger asthmatic reactions. Researchers’ next hope to determine which microbes are most responsible for preventing asthma — and that, perhaps, may lead to new therapies, such as targeted microbe exposures, for the dreaded respiratory malady.

More broadly, the study is a reminder that humans have been living and fighting off germs for tens of thousands of years. Particularly when we’re young, germs serve an important purpose for the development of the immune system. By depriving our children of exposure to germs, we may be depriving them the benefits of a process the human body has evolved over aeons, a process that helps to create healthy and allergy-free adults.

January 9, 2012

DARPA appoints former astronaut to lead 100-year starship project

Filed under: Space, Technology, USA — Tags: , , , — Nicholas @ 09:56

Brid-Aine Parnell works the Star Trek angle on the appointment of former NASA astronaut Dr Mae Jemison as the head of the 100-year Starship project:

The agency had not responded to a request for comment at the time of publication, and has not yet announced the appointment publicly.

Dr Jemison, who has a degree in chemical engineering and a doctorate in medicine, was the science mission specialist on the STS-47 Spacelab-J in 1992 and logged over 190 hours in space.

As well as being a bona fide boffin, Jemison also spent time in the IT trenches, working in computer programming, among other things, before joining NASA.

She’s also no stranger to the ideas behind a starship, since, as a long-time Star Trek fan, she had a bit part in one episode of Star Trek: The Next Generation.

The episode, entitled Second Chances, must surely go down as evidence of her remarkable patience and forbearance, since it featured the two most irritating TNG characters, Commander Riker and Deanna Troi, rather prominently.

December 30, 2011

Are creative people also more likely to be “creative” with the truth?

Filed under: Science — Tags: , , , — Nicholas @ 10:51

Melissa Leong on a recent study:

Francesca Gino’s new study, which links creativity to dishonesty, opens with a quote from 18th-century French philosopher and art critic Denis Diderot: “Evil always turns up in this world through some genius or other.”

Gino is not suggesting, as some artists at the time complained, that creative people are evil. But she is saying that, according to her research, creative people are more apt to cheat, lie and justify their evil. Gino, associate professor of business administration at Harvard University, spoke to the Post about her study, co-authored by Dan Ariely, a behavioural economist at Duke University. (Their findings were published in the Journal of Personality and Social Psychology last month.)

December 6, 2011

Guardian study finds that August rioters were motivated by Guardian editorials

Filed under: Britain, Economics, Government, Law, Media — Tags: , , , — Nicholas @ 09:16

Brendan O’Neill on the recent study, carried out by the London School of Economics and the Guardian:

Well, that’s convenient, isn’t it? A four-month Guardian/London School of Economics study into the riots that rocked English cities in August has found that the rioters were pretty much Guardian editorials made flesh. Concerned about government cuts, annoyed by unfair policing, shocked by social inequality and outraged by the MPs’ expenses scandal, it seems the young men and women who looted shops and burnt down bus stops weren’t Thatcher’s children after all — they were Rusbridger’s children, the moral offspring of those moral guardians of chattering-class liberalism.

This is a blatant case of advocacy research, of researchers finding what they wanted to find, or at least desperately hoped to find. For months now, the Guardian has been publishing articles arguing that the rioters were politically motivated, under headlines such as ‘These riots were political’ and with claims such as ‘the looting was highly political’ and the riots were a protest against ‘brutal cuts and enforced austerity measures’. And now, lo and behold, a Guardian study, Reading the Riots, has discovered that the rioters were indeed ‘rebels with a cause’, with 86 per cent of the 270 rioters interviewed claiming the violence was caused by poverty, 85 per cent arguing that policing was the big issue, and 80 per cent saying they were riled by government policies. Reading this study, we are left to marvel either at the extraordinary perspicacity of Guardian writers, or at their ability to carry out research in such a way that it confirms their own political preconceptions.

This study looks less like a cool-headed, neutral piece of sociology, and more like a semi-conscious piece of political ventriloquism, where rioters have been coaxed to mouth the political beliefs of the middle-class commentariat. This is not to say the Guardian and LSE researchers have been purposely deceitful, inventing evidence to suit a political thesis. Advocacy research is more subtle and less conscious than that. It involves a kind of inexorable pursuit of facts that fit and evidence that helps bolster a pre-existing conviction. So mental-health charities keen to garner greater press coverage always find high levels of mental illness, children’s charities that want to raise awareness about child abuse always find rising levels of child neglect, and now Guardian researchers who want to show that they’re right to fret about Lib-Con policies and outdated policing have found that these are burning issues amongst volatile English yoof, too.

December 5, 2011

Moral hazard invades the scientific sphere

Filed under: Economics, Government, Media, Science — Tags: , , — Nicholas @ 12:23

Bill Frezza looks at an unanticipated consequence of pouring more government money into the sciences:

Science and the scientific method are the jewels in the crown of Western civilization. The ascertainment of facts, construction of reproducible experiments, development of falsifiable theories, impartial training and meritocratic advancement of practitioners, and — most importantly — integrity of the publication process by which a well established body of truth can be confidently assembled all underpin the respect accorded to science by the citizenry. In modern times, this respect translates into tax dollars.

Unfortunately, today those tax dollars are corrupting the process. Unprecedented billions are doled out by unaccountable federal and state bureaucracies run by and for the benefit of a closed guild of practitioners. This has created a moral hazard to scientific integrity no less threatening than the moral hazard to financial integrity that recently destroyed our banking system.

According to a report in Nature Reviews Drug Discovery, nearly two-thirds of the experimental results published in peer-reviewed journals could not be reproduced in Bayer’s labs. The latest special issue of Science is devoted to the growing problem of irreproducibility. The Wall Street Journal reports that Amgen, Pfizer, and others have abandoned research programs after spending hundreds of millions pursuing academic research that could never be replicated.

H/T again to Monty for the link.

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