Rowan Jacobsen profiles the scientist who believes, based on her own research, that the Wuhan Coronavirus was not a naturally occurring mutation and was instead deliberately created in a Chinese government lab:
It wasn’t long before she came across an article about the remarkable stability of the virus, whose genome had barely changed from the earliest human cases, despite trillions of replications. This perplexed Chan. Like many emerging infectious diseases, COVID-19 was thought to be zoonotic — it originated in animals, then somehow found its way into people. At the time, the Chinese government and most scientists insisted the jump had happened at Wuhan’s seafood market, but that didn’t make sense to Chan. If the virus had leapt from animals to humans in the market, it should have immediately started evolving to life inside its new human hosts. But it hadn’t.
On a hunch, she decided to look at the literature on the 2003 SARS virus, which had jumped from civets to people. Bingo. A few papers mentioned its rapid evolution in its first months of existence. Chan felt the familiar surge of puzzle endorphins. The new virus really wasn’t behaving like it should. Chan knew that delving further into this puzzle would require some deep genetic analysis, and she knew just the person for the task. She opened Google Chat and fired off a message to Shing Hei Zhan. He was an old friend from her days at the University of British Columbia and, more important, he was a computational god.
“Do you want to partner on a very unusual paper?” she wrote.
Sure, he replied.
One thing Chan noticed about the original SARS was that the virus in the first human cases was subtly different — a few dozen letters of genetic code — from the one in the civets. That meant it had immediately morphed. She asked Zhan to pull up the genomes for the coronaviruses that had been found on surfaces in the Wuhan seafood market. Were they at all different from the earliest documented cases in humans?
Zhan ran the analysis. Nope, they were 100 percent the same. Definitely from humans, not animals. The seafood-market theory, which Chinese health officials and the World Health Organization espoused in the early days of the pandemic, was wrong. Chan’s puzzle detectors pulsed again. “Shing,” she messaged Zhan, “this paper is going to be insane.”
In the coming weeks, as the spring sun chased shadows across her kitchen floor, Chan stood at her counter and pounded out her paper, barely pausing to eat or sleep. It was clear that the first SARS evolved rapidly during its first three months of existence, constantly fine-tuning its ability to infect humans, and settling down only during the later stages of the epidemic. In contrast, the new virus looked a lot more like late-stage SARS. “It’s almost as if we’re missing the early phase,” Chan marveled to Zhan. Or, as she put it in their paper, as if “it was already well adapted for human transmission.”
That was a profoundly provocative line. Chan was implying that the virus was already familiar with human physiology when it had its coming-out party in Wuhan in late 2019. If so, there were three possible explanations.
For the record, my strong suspicion is that she is correct about the origins of the virus, but I don’t think it was deliberately released by the Chinese government. I think if it had been deliberate, it would have been much more directly “weaponized” in both delivery mechanism and targeting.
