Quotulatiousness

October 16, 2013

Cocaine and heroin are less addictive than Oreos

Filed under: Food, Health, Science — Tags: , , — Nicholas @ 13:51

in lab rats, anyway:

“Research Shows Oreos Are Just As Addictive As Drugs,” says the headline above a recent Connecticut College press release. “…in Lab Rats,” it adds, and I’ll get to that part later. But first note that the study’s findings could just as truthfully be summarized this way: “Drugs Are No More Addictive Than Oreos.” The specific drugs included in the study were cocaine and morphine, which is what heroin becomes immediately after injection. So the headline also could have been: “Research Shows That Heroin and Cocaine Are No More Addictive Than Oreos.” Putting it that way would have raised some interesting questions about the purportedly irresistible power of these drugs, which supposedly justifies using force to stop people from consuming them.

[…]

So what exactly did the rats do? They favored the side of a maze where they were given Oreos to the same extent that they favored that side of the maze when they were given an injection of cocaine or morphine there. Furthermore, when the researchers “used immunohistochemistry to measure the expression of a protein called c-Fos, a marker of neuronal activation, in the nucleus accumbens, or the brain’s ‘pleasure center,'” they found that “the Oreos activated significantly more neurons than cocaine or morphine.” Given the latter finding, perhaps we should credit Connecticut College’s publicity department with restraint for not announcing that Oreos are in fact more addictive than cocaine or heroin. Or to put it another way: Cocaine and heroin are less addictive than Oreos. Which makes you wonder why people go to prison for selling the drugs but not for selling the cookies, especially since Oreos and similar foods “may present even more of a danger.”

The idea that people can take or leave cocaine or heroin in the same way they can take or leave Oreos seems inconsistent with research that supposedly shows how powerfully reinforcing these substances are. Studies published between 1969 and 1985, for instance, found that rats and rhesus monkeys “will prefer cocaine to food” and “will self-administer cocaine until death or near-death,” as Stanton Peele and Richard DeGrandpre note in a 1998 Addiction Research article. But the animals in these studies were isolated from other animals, deprived of interesting stimuli, and prevented from engaging in normal behavior while tethered to catheters providing “an unlimited, direct flow of high concentrations of cocaine at all times at little or no cost” (in terms of effort). Research conducted in more naturalistic settings finds that monkeys and rats are much more apt to consume cocaine and morphine in moderation.

Laboratory animals’ tendency to consume drugs to excess when they are bored and lonely has pretty clear parallels in human behavior. But unlike rats and monkeys, humans are capable of reason and foresight (even if they do not always exercise those faculties) as well as emotions such as guilt and regret. They also have considerable control over their own environments. If the reinforcing power of drugs is not the only factor in addiction among rats and monkeys, it surely is not a complete explanation for why some people get hooked on these substances while most do not.

US wages and personal mobility

Filed under: Economics, USA — Tags: , , , , — Nicholas @ 08:07

Coyote Blog looks at the widely touted flattening of income growth in the United States and wonders how much mobility (people moving from one state to another) might play a part in the overall picture:

All of this is a long introduction to some thinking I have been doing on all the “Average is Over” discussion talking about the flattening of growth in median wages. I begin with this chart:

Click to see full-sized image

Click to see full-sized image

There is a lot of interstate migration going on. And much of it seems to be out of what I think of as higher cost states like CA, IL, and NY and into lower cost states like AZ, TX, FL, and NC. One of the facts of life about the CPI and other inflation adjustments of income numbers is that the US essentially maintains one average CPI. Further, median income numbers and poverty numbers tend to assume one single average cost of living number. But everyone understands that the income required to maintain lifestyle X on the east side of Manhattan is very different than the income required to maintain lifestyle X in Dallas or Knoxville or Jackson, MS.

Could it be that even with a flat average median wage, that demographic shifts to lower cost-of-living states actually result in individuals being better off and living better?

For some items one buys, of course, there is no improvement by moving. For example, my guess is that an iPhone with a monthly service plan costs about the same anywhere you go in the US. But if you take something like housing, the differences can be enormous.

Let’s compare San Francisco and Houston. At first glance, San Francisco seems far wealthier. The median income in San Francisco is $78,840 while the median income in Houston in $55,910. Moving from a median wage job in San Francisco to a media wage job in Houston seems to represent a huge step down. If you and a bunch of your friends made this move, the US median income number would drop. It would look like people were worse off.

But something else happens when you take this nominal pay cut to move to Houston. You also can suddenly afford a much nicer, larger house, even at the lower nominal pay. In San Francisco, your admittedly higher nominal pay would only afford you the ability to buy only 14% of the homes on the market. And the median home, which you could not afford, has only about 1000 square feet of space. In Houston, on the other hand, your lower nominal pay would allow you to buy 56% of the homes. And that median home, which you can now afford, will have on average 1858 square feet of space.

Cultural organizations and unions

Filed under: Economics, Media — Tags: , , , , — Nicholas @ 07:41

Richard Epstein looks at two recent disputes between unionized employees and cultural organizations:

This past week featured two stories about major orchestras dealing with their adamant unions. The first incident occurred on Wednesday, October 2 at Carnegie Hall in New York City. A fancy opening night gala, featuring the violinist Joshua Bell and the young jazz performer Esperanza Spalding, was called off due to a surprise strike by Local One of the International Alliance of Theatrical Stage Employees.

The second dispute, still unresolved, involves the protracted labor impasse at the Minnesota Orchestra. On October 1, true to his promise, star music director Osmo Vänskä resigned because of the inability of the orchestra and its musicians’ union to hammer out a new contract in time to prepare for concerts scheduled at Carnegie Hall on November 2 and 3. The issues in these two labor disputes could scarcely be more different. But each of them, in its own way, illustrates the long-term toll that American labor law takes on the cultural lifeblood of our nation.

The incident at Carnegie Hall raised more than a few eyebrows when it was revealed that the strike was organized by the five full-time Carnegie Hall stagehands who were members of Local One. Their annual compensation in wages and overtime averaged a cool $419,000 per year, making them — one properties manager, two carpenters, and two electricians — five of the seven highest paid workers at Carnegie Hall after Carnegie CEO Clive Gillenson. Other union members in unspecified numbers were called in to help from time to time, presumably at rates on par with those Carnegie Hall paid to its full time workers.

As befits the sorry state of labor relations in the United States, the dispute was not about the status of these five workers. Rather, it focused on the new jobs that would open upon the completion of a new education wing in 2015. Mr. Gillenson was not exactly breathing fire when, well-coached in the pitfalls of labor law, he eschewed any anti-union sentiment and announced that he expected union workers to take the stagehand slots in that new facility. It was just that he insisted on dealing with unions that lacked the clout and the wages of the hardy men from Local One.

[…]

The bargaining dynamics could not have been more different in the Minnesota dispute. It is no secret that unionized musicians command a short-run monopoly premium for their members. The orchestra knows that it can earn back some fraction of that wage premium by securing the most talented musicians. But by the same token, any generous deal opens the orchestra up to financial ruin if its endowment shrinks or if its key donors cut back their support in hard times. But usually the large gains for older musicians carry the day.

Unions in all industries — think of the debacle at General Motors — do not do well in negotiating givebacks to management. Yet, ironically, the higher the premium that unions are able to extract during good times, the larger the give-backs are needed to bring the employer’s fiscal position into balance during bad times.

Just that dynamic was in play with the Minnesota Orchestra. The high wages before 2009 led to one round of union concessions. But in 2011, the budget was still out of balance, and management came back with a request for further cuts of about 32 percent. It later softened its demands to insist on wage cuts that would reach 25 percent after three years. Those cuts would be offset by a one time $20,000 bonus, which would, of course, not be part of the wage base in future years.

The union proposals were for pay cuts in the range of six to eight percent. This would have left an annual deficit in the order of $6 million. In the end, no deal could be reached, which precipitated Vänskä’s departure and the subsequent huge hit to prestige of the orchestra’s hard-earned international reputation.

If everyone followed these rules, Facebook would be 1/8th the size it is

Filed under: Media — Tags: , , — Nicholas @ 06:54

Brendan McKenna linked to this Huffington Post piece, providing a gentle reminder to too many Facebook users about their insufferable posting habits:

To be unannoying, a Facebook status typically has to be one of two things:

1) Interesting/Informative

2) Funny/Amusing/Entertaining

You know why these are unannoying? Because things in those two categories do something for me, the reader. They make my day a little better.

Ideally, interesting statuses would be fascinating and original (or a link to something that is), and funny ones would be hilarious. But I’ll happily take mildly amusing — at least we’re still dealing with the good guys.

On the other hand, annoying statuses typically reek of one or more of these five motivations:

1) Image Crafting. The author wants to affect the way people think of her.

2) Narcissism. The author’s thoughts, opinions, and life philosophies matter. The author and the author’s life are interesting in and of themselves.

3) Attention Craving. The author wants attention.

4) Jealousy Inducing. The author wants to make people jealous of him or his life.

5) Loneliness. The author is feeling lonely and wants Facebook to make it better. This is the least heinous of the five — but seeing a lonely person acting lonely on Facebook makes me and everyone else sad. So the person is essentially spreading their sadness, and that’s a shitty thing to do, so it’s on the list.

Facebook is infested with these five motivations — other than a few really saintly people, most people I know, myself certainly included, are guilty of at least some of this nonsense here and there. It’s an epidemic.

QotD: Shylock on revenge

Filed under: Media, Quotations, Religion — Tags: , , , — Nicholas @ 00:01

Hath not a Jew eyes? Hath not a Jew hands, organs, dimensions, senses, affections, passions; fed with the same food, hurt with the same weapons, subject to the same diseases, heal’d by the same means, warm’d and cool’d by the same winter and summer as a Christian is? If you prick us, do we not bleed? If you tickle us, do we not laugh? If you poison us, do we not die? And if you wrong us, shall we not revenge? If we are like you in the rest, we will resemble you in that. If a Jew wrong a Christian, what is his humility? Revenge. If a Christian wrong a Jew, what should his sufferance be by Christian example? Why, revenge. The villainy you teach me, I will execute, and it shall go hard but I will better the instruction.

William Shakespeare, The Merchant of Venice, Act III Scene 1.

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